Outcome of Surfactant replacement therapy for respiratory distress syndrome in preterm babies

Introduction: Surfactant is an important treatment modality in preterm babies with respiratory distress syndrome leading to decrease mortality, morbidity and cost of treatment. Experiences on surfactant therapy Nepal are scarce. This study was conceptualised find the use immediate outcome a tertiary care hospital Nepal. Methods: A cross-sectional done who received over period five years at neonatal / pediatric intensive unit Patan Hospital, Lalitpur, After approval from Institutional review committee, information gestational age, sex, birth weight, doses dexamethasone, time delivery, complications retrieved files. Comparison between early late rescue group done. Data analysed using SPSS 16. Results: Twelve (11.2%) needed repeat dose surfactant. Only 12 About 53 (49.5%) developed hypotension being most common seen 38 (35.5%) babies. Complications were 75% 46% respectively (p - 0.22). The mortality inversely proportional age 0.002) weight < 0.05). Mortality 16% both groups but deaths related all group. Conclusions: more similar groups, weight.